It is not stable at high temperatures. Vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer called angiosarcoma. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. Vinyl chloride … Vinyl Chloride 75-01-4 _____ Hazard Summary . Primary exposure to vinyl chloride occurs through inhalation. Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. Studies in workers who inhale vinyl chloride over many years show an increased risk of … Vinyl Chloride 1. This fact sheet discusses possible health risks from exposure to low levels of vinyl chloride typically found in drinking water wells. The odds ratio (OR) for ever exposure to vinyl chloride was 1.05 (95% confidence interval, CI: 0.68-1.62) and a modest, non-significant increase in the risk of lung cancer was found in the highest exposed subgroup. A statement of each employee's suitability for continued exposure to vinyl chloride including use of protective equipment and respirators, shall be obtained from the examining physician promptly after any examination. September 2015 Vinyl Chloride What is vinyl chloride? The U.S. Environmental Protection Agency has set a maximum contaminant level of 2 ppb of vinyl chloride for public drinking water supplies. PREFACE. Vinyl chloride is a synthetic, colorless gas. One reason why PVC is so toxic is that it is often mixed with softening chemicals called plasticizers, the most well known variety being phalates. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. References: cancer.gov, OSHA, IARC, CDC Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. 5. Prolonged exposure can cause cancer in the liver, brain, blood and lungs. If vinyl chloride is detected in your water, contact your local or state health department. Under the authority of the Federal Advisory Committee Act (FACA) P.L. Acute Exposure Guideline Levels. Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system (CNS) effects, such as … (1,2) Assessing Personal Exposure Vinyl chloride can be detected in urine and body tissues, but the tests are not reliable indicators of total exposure. It burns easily. Most vinyl chloride is used to make polyvinyl chloride (PVC) plastic and vinyl products. Exposure Sources of Vinyl Chloride. 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